Education:
1985 - MD - Albert Einstein College of Medicine, Bronx, NY
1981 - BA - Biology - Boston University, Boston, MA
Board Certifications:
American Board of Internal Medicine
Training:
1994 - Clinical and Research Fellowship - Nephrology - University of Pennsylvania School of Medicine, Philadelphia, PA
Highlights:
08/2017-present Professor, Division Chief of Nephrology, University of Texas Health San Antonio
08/2017-present Vice Chair, Research Department of Medicine, UTHSA
08/2017-present David L. Hillis Endowed Distinguished Chair in Medicine, UTHSA
06/2018-present Director, Center for Renal Precision Medicine, UTHSA
2020 Governor’s Chronic Kidney Disease Task Force, Texas
Appointments:
04/2018-Present - Member of Institutional Core Committee - UTHSA
02/2020-present - Chief, Search Committee for Division Chief in Endocrinology - UTHSA
1. Precision medicine for kidney disease
2. Precision health care delivery systems for diabetes, obesity and CKD
3. Systems biology approaches for chronic disease
4. Novel therapies for progressive kidney disease
5. Mitochondrial function in health and disease
6. Cytokine signaling in diabetic kidney disease
Grants:
NIDDK, UG3-UH3 DK114920 Tissue Interrogation Site for Kidney Precision Medicine Project, 07/01/2017-06/30/2022
NIDDK, RFA-DK-16-028 Central Hub for Kidney Precision Medicine Project (PI: Himmelfarb, J, Co-I: Sharma), 07/01/2017-06/30/2022
CDMRP PR181598 Multi-Omics and Mitochondrial Dysfunction in Acute Lung Injury (PI: Sharma), 2019-2022
VA Merit Award, Novel Mechanisms of Renal Injury, (PI: Sharma), 2016-2020
NIDDK, R24DK0824841-07 (PI: Feldman UMichigan, Subcontract to UCSD, PI: Sharma) Integrated Systems Biology Approach to Diabetic Microvascular Complications, 2016-2021
NIDDK, RO1 DK110541-01, (PI: Natarajan UCSD, Co-I: Sharma), Developing and Validating Prognostic Metabolomic Signatures of Diabetic Kidney Disease, 2017-2022
JDRF Network Grant: Discovery and Validation of Prognostic Biomarkers of Renal Function Decline in Type 1 Diabetes, (PI: Sharma), 2015-2020
New Zealand, DUNEDIN Study of Aging in New Zealand Population, (PI:Poulson, New Zealand) (Subcontract to UCSD, PI:Sharma), 2016-2021
80/20 Foundation Award: Precision Metabolic and Molecular Mechanisms of Low Carbohydrate and Ketogenic Diet (PI: Sharma), 2020-2022
Han X, Shi Y, Diamond-Stanic M, Sharma K. Role of Mitochondria in the Regulation of Kidney Function and Metabolism in Type 2 Diabetes. Chapter 12 in Mitochondria in Obesity and Type 2 Diabetes, edited by Béatrice Morio, Michel Rigoulet and Luc Pénicaud, published by Elsevier. In press, 2019.
Bhattarai M, Madesh M, Sharma K. Oxidative Stress and Anti-Oxidants. Chapter in Seldin and Giebisch’s The Kidney: Physiology & Pathophysiology, 6th Edition, edited by Robert Alpern, Orson Moe, Michael Caplan, and Susan Quaggin. For 2020.